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Browsing by Subject "Glucocorticoid induced osteoporosis"

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Bone matrix development in steroid-induced osteoporosis is associated with a consistently reduced fibrillar stiffness linked to altered bone mineral quality

Xi, L; Falco, PD; Barbieri, E; Karunaratne, A; Bentley, L; Esapa, CT; Terrill, NJ; Brown, SDM; Cox, RD; Davis, GR; Pugno, NM; Thakker, RV; Gupta, HS [Article-Full-text]

Glucocorticoid-induced osteoporosis (GIOP) is a major secondary form of osteoporosis, with the fracture risk significantly elevated - at similar levels of bone mineral density - in patients taking glucocorticoids compared ...
Investigation of bone matrix composition, architecture and mechanical properties reflect structure-function relationship of cortical bone in glucocorticoid induced osteoporosis

Xi, L; Song, Y; Wu, W; Qu, Z; Wen, J; Liao, B; Tao, R; Ge, J; Fang, D [Article-Full-text]

Glucocorticoid induced osteoporosis (GIOP) is the most common negative consequence of long-term glucocorticoid treatment, leading to increased fracture risk followed by loss of mobility and high mortality risk. These ...
Mechanical response of cortical bone in compression and tension at the mineralized fibrillar level in steroid induced osteoporosis

Xi, L; Wen, W; Wu, W; Qu, Z; Tao, R; Karunaratne, A; Liao, B; Li, Y; Fang, D [Article-Full-text]

Nanocomposites like bone are used in vivo in a dynamic mechanical environment, and musculoskeletal fracture during traumatic events lead to pain and immobilisation, especially significant in elderly and patients with ...
Reduction of fibrillar strain-rate sensitivity in steroid-induced osteoporosis linked to changes in mineralized fibrillar nanostructure

Xi, L; De Falco, P; Barbieri, E; Karunathilake, A; Bentley, L; Esapa, CT; Davis, GR; Terrill, NJ; Cox, RD; Pugno, NM; Thakker, RV; Weinkamer, R; Wu, WW; Fang, DN; Gupta, HS [Article-Full-text]

As bone is used in a dynamic mechanical environment, understanding the structural origins of its time-dependent mechanical behaviour - and the alterations in metabolic bone disease - is of interest. However, at the scale ...

Browsing by Subject "Glucocorticoid induced osteoporosis"

Browsing by Subject "Glucocorticoid induced osteoporosis"

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